Metformin Hydrochloride Extended Release Tablets + Ranolazine Interaction

Majorinteraction on record

Description

OCT2/MATE inhibitor that reduces metformin clearance, increasing systemic exposure and risk for lactic acidosis.

Mechanism

Interferes with renal tubular transport systems (OCT2/MATE) involved in metformin elimination

Source: NLP:metformin hydrochloride extended-release tablets

Related drug profiles

All Metformin Hydrochloride Extended Release Tablets interactions →All Ranolazine interactions →
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