Meropenem And Sodium Chloride + Probenecid Interaction

Majorinteraction on record

Description

Probenecid competes with meropenem for active tubular secretion, resulting in increased plasma concentrations of meropenem. Coadministration is not recommended.

Mechanism

Competes for active tubular secretion in the kidney

Source: NLP:meropenem and sodium chloride