Mercaptopurine + Febuxostat Tablets 40 Mg Interaction
Contraindicatedinteraction on record
Description
Febuxostat is contraindicated with mercaptopurine. Concomitant use could increase plasma concentrations resulting in severe toxicity.
Mechanism
Febuxostat inhibits xanthine oxidase, the enzyme that metabolizes mercaptopurine
Source: NLP:febuxostat tablets 40 mg