Mercaptopurine + Doxorubicin Hydrochloride Interaction
Majorinteraction on record
Description
Doxorubicin may potentiate 6-mercaptopurine-induced hepatotoxicity, resulting in hepatic dysfunction with elevated bilirubin, alkaline phosphatase, and transaminases.
Mechanism
Potentiation of hepatotoxicity
Source: NLP:doxorubicin hydrochloride