Mercaptopurine + Doxorubicin Interaction
Majorinteraction on record
Description
Doxorubicin may potentiate 6-mercaptopurine-induced hepatotoxicity, resulting in hepatic dysfunction manifested by increased total serum bilirubin, alkaline phosphatase, and aspartate aminotransferase.
Mechanism
Potentiation of 6-mercaptopurine-induced hepatotoxicity
Source: NLP:doxorubicin