Mao Inhibitors + Nilotinib Interaction
Majorinteraction on record
Description
Concomitant use increases nilotinib concentrations, which may increase the risk of nilotinib toxicities. Avoid concomitant use or reduce nilotinib dose if coadministration cannot be avoided.
Mechanism
Inhibition of CYP3A-mediated metabolism of nilotinib
Source: NLP:nilotinib