Lumacaftor And Ivacaftor + St Johns Wort Interaction

Majorinteraction on record

Description

Strong CYP3A inducer significantly reduces ivacaftor exposure and ORKAMBI therapeutic effectiveness. Co-administration not recommended.

Mechanism

CYP3A induction

Source: NLP:lumacaftor and ivacaftor

Related drug profiles

All Lumacaftor And Ivacaftor interactions →All St Johns Wort interactions →
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