Losartan Potassium And Hydrochlorothiazide + Aliskiren Interaction
Majorinteraction on record
Description
Dual blockade of the renin-angiotensin system is associated with increased risks of hypotension, syncope, hyperkalemia, and changes in renal function including acute renal failure.
Mechanism
Dual RAS blockade increases adverse effects compared to monotherapy
Source: NLP:losartan potassium and hydrochlorothiazide