Lonapegsomatropin Tcgd + Prednisone Interaction
Moderateinteraction on record
Description
SKYTROFA inhibits 11βHSD-1, reducing conversion of prednisone to active metabolites. Patients on glucocorticoid replacement may require increased maintenance or stress doses.
Mechanism
Inhibition of microsomal enzyme 11β-hydroxysteroid dehydrogenase type 1 (11βHSD-1)
Source: NLP:lonapegsomatropin-tcgd