Lisdexamfetamine Dimesylate Capsules + Mao Inhibitors Interaction

Contraindicatedinteraction on record

Description

MAOI antidepressants slow amphetamine metabolism, increasing norepinephrine release and causing hypertensive crisis, toxic neurological effects, and potentially fatal malignant hyperpyrexia.

Mechanism

Slow amphetamine metabolism, increasing release of norepinephrine and monoamines from adrenergic nerve endings

Source: NLP:lisdexamfetamine dimesylate capsules