Liothyronine Sodium + Carbamazepine Interaction

Moderateinteraction on record

Description

May cause protein binding site displacement of thyroid hormones, reducing serum protein binding. Total and free T4 may be reduced 20-40%, but most patients remain clinically euthyroid. Closely monitor thyroid hormone parameters.

Mechanism

Reduced serum protein binding of thyroid hormones

Source: NLP:liothyronine sodium