Levothyroxine Sodium + Salicylates 2 Gday Interaction

Moderateinteraction on record

Description

Inhibit binding of T4 and T3 to thyroxine-binding globulin and transthyretin. Initial increase in FT4 followed by return to normal with sustained use, though total T4 may decrease up to 30%.

Mechanism

Inhibition of T4 and T3 binding to thyroxine-binding globulin and transthyretin

Source: NLP:levothyroxine sodium