Levonorgestrelethinyl Estradiol And Ethinyl Estradiol + Lamotrigine Interaction

Majorinteraction on record

Description

COCs significantly decrease plasma concentrations of lamotrigine, which may reduce seizure control and require dosage adjustments.

Mechanism

Induction of lamotrigine glucuronidation

Source: NLP:levonorgestrel / ethinyl estradiol and ethinyl estradiol