Levoleucovorin Injection + Phenytoin Interaction
Moderateinteraction on record
Description
Folic acid in large amounts may counteract antiepileptic effect and increase seizure frequency. Monitor patients taking folinic acid with antiepileptic drugs.
Mechanism
Folic and folinic acids share common metabolic pathways that may interfere with antiepileptic drug efficacy
Source: NLP:levoleucovorin injection