Letermovir + Cyclosporine Interaction
Moderateinteraction on record
Description
Co-administration requires dosage adjustment of letermovir to 240 mg once daily in adults and pediatric patients ≥12 years; dose adjustment may be needed in younger patients.
Mechanism
Cyclosporine affects letermovir plasma concentrations and the magnitude of CYP3A and OATP1B1/3-mediated interactions
Source: NLP:letermovir