Ledipasvir And Sofosbuvir + St Johns Wort Interaction

Majorinteraction on record

Description

P-gp inducer that may decrease ledipasvir and sofosbuvir plasma concentrations, leading to reduced therapeutic effect. Use is not recommended.

Mechanism

P-gp induction decreases ledipasvir and sofosbuvir concentrations

Source: NLP:ledipasvir and sofosbuvir