Larotrectinib + St. John'S Wort Interaction

Majorinteraction on record

Description

Strong CYP3A4 inducer; coadministration may decrease larotrectinib plasma concentrations and decrease efficacy. Avoid coadministration.

Mechanism

CYP3A4 induction

Source: NLP:larotrectinib

Related drug profiles

All Larotrectinib interactions →All St. John'S Wort interactions →
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