Lamotrigine + Desogestrel And Ethinyl Estradiol And Ethinyl Estradiol Interaction

Majorinteraction on record

Description

Combined hormonal contraceptives significantly decrease plasma concentrations of lamotrigine, which may reduce seizure control; dosage adjustments may be necessary.

Mechanism

Induction of lamotrigine glucuronidation

Source: NLP:desogestrel and ethinyl estradiol and ethinyl estradiol