Ioversol + Metformin Interaction
Majorinteraction on record
Description
Iodinated contrast agents increase risk of metformin-induced lactic acidosis, possibly through worsening renal function. Stop metformin at or prior to IOVERSOL administration in patients with eGFR 30-60 mL/min/1.73 m² or with hepatic impairment, alcoholism, or heart failure.
Mechanism
Possible worsening of renal function
Source: NLP:ioversol