Iohexol + Metformin Interaction
Majorinteraction on record
Description
Iodinated contrast agents increase risk of metformin-induced lactic acidosis, possibly by worsening renal function. Stop metformin at or prior to IOHEXOL administration in patients with eGFR 30-60 mL/min/1.73m², hepatic impairment, alcoholism, heart failure, or intra-arterial contrast use.
Mechanism
Worsening renal function
Source: NLP:iohexol