Iodixanol + Metformin Interaction
Majorinteraction on record
Description
Iodixanol may increase risk of metformin-induced lactic acidosis, possibly by worsening renal function. Stop metformin prior to iodixanol administration in patients with eGFR 30-60 mL/min/1.73 m² or hepatic impairment, alcoholism, or heart failure.
Mechanism
Worsening of renal function
Source: NLP:iodixanol