Glecaprevir And Pibrentasvir + Carbamazepine Interaction
Majorinteraction on record
Description
May significantly decrease plasma concentrations of glecaprevir and pibrentasvir, leading to reduced therapeutic effect. Coadministration is not recommended.
Mechanism
Induces P-gp and CYP3A
Source: NLP:glecaprevir and pibrentasvir