Furosemide Benzalkonium Chloride + Methotrexate Interaction

Moderateinteraction on record

Description

Methotrexate and other drugs undergoing significant renal tubular secretion may reduce the effect of furosemide and furosemide may decrease renal elimination of these drugs, potentially causing toxicity.

Mechanism

Competition for renal tubular secretion

Source: NLP:furosemide, benzalkonium chloride