Fosinopril Sodium And Hydrochlorothiazide + Lithium Interaction
Majorinteraction on record
Description
Risk of lithium toxicity increased due to reduced renal clearance from both ACE inhibitor and thiazide components; frequent serum lithium level monitoring recommended.
Mechanism
ACE inhibitors increase serum lithium levels; thiazide diuretics reduce renal clearance of lithium
Source: NLP:fosinopril sodium and hydrochlorothiazide