Fluoxetine + Imipramine Pamoate Interaction
Moderateinteraction on record
Description
SSRI that inhibits P450 2D6 and hepatic enzymes, increasing imipramine plasma concentrations. At least 5 weeks may be necessary before initiating imipramine after fluoxetine withdrawal due to long half-life.
Mechanism
P450 2D6 and hepatic enzyme inhibition
Source: NLP:imipramine pamoate