Fluoxetine + Dextroamphetamine Saccharate Amphetamine Aspartate Monohydra Interaction

Majorinteraction on record

Description

CYP2D6 inhibitor and serotonergic drug that increases amphetamine exposure and risk of serotonin syndrome. Initiate with lower doses and monitor for serotonin syndrome.

Mechanism

CYP2D6 inhibition increases amphetamine exposure; serotonergic interaction increases serotonin syndrome risk

Source: NLP:dextroamphetamine saccharate, amphetamine aspartate, dextroamphetamine sulfate and amphetamine sulfate