Fluorouracil + Allopurinol Interaction

Majorinteraction on record

Description

Allopurinol may decrease anti-tumor activity due to suppression of phosphorylation of 5-fluorouracil. Concomitant administration should be avoided.

Mechanism

Suppression of phosphorylation of 5-fluorouracil

Source: NLP:allopurinol

Related drug profiles

All Fluorouracil interactions →All Allopurinol interactions →
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