Finerenone + Sensitive Cyp3a Substrates Interaction

Moderateinteraction on record

Description

Finerenone 40 mg is a weak CYP2C8 inhibitor and increases exposure of CYP2C8 substrates; monitor patients more frequently for adverse reactions.

Mechanism

Finerenone weakly inhibits CYP2C8 at 40 mg dose

Source: NLP:finerenone