Estradiol Valerate And Estradiol Valeratedienogest + Fluconazole Interaction
Moderateinteraction on record
Description
[See Clinical Pharmacology (12.3).] Substances Increasing the Systemic Exposure of COCs (enzyme inhibitors): Concomitant administration of moderate or strong CYP3A4 inhibitors like azole antifungals (for example, ketoconazole, itraconazole, voriconazole, fluconazole), verapamil, macrolides (for example, clarithromycin, erythromycin), diltiazem, and grapefruit increase the serum concentrations of both estradiol and dienogest.
Source: FDA drug label - estradiol valerate and estradiol valerate/dienogest