Ertugliflozin And Metformin Hydrochloride + Cimetidine Interaction

Majorinteraction on record

Description

Increases risk of lactic acidosis by reducing metformin clearance through OCT2/MATE inhibition.

Mechanism

Inhibition of organic cationic transporter-2 and multidrug and toxin extrusion transporters

Source: NLP:ertugliflozin and metformin hydrochloride

Related drug profiles

All Ertugliflozin And Metformin Hydrochloride interactions →All Cimetidine interactions →
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