Enalapril Maleate + Indomethacin Interaction

Majorinteraction on record

Description

NSAID that may result in deterioration of renal function and diminish antihypertensive effect of enalapril, especially in elderly, volume-depleted, or renally compromised patients.

Mechanism

Reduced renal blood flow and antagonism of antihypertensive effect

Source: NLP:enalapril maleate