Emtricitabine Rilpivirine And Tenofovir Disoproxil Fumarate + Nsaids Interaction

Moderateinteraction on record

Description

High-dose or multiple NSAIDs coadministration may increase serum concentrations of emtricitabine, tenofovir, and/or NSAIDs due to competition for renal tubular secretion.

Mechanism

NSAIDs compete for active tubular secretion

Source: NLP:emtricitabine, rilpivirine hydrochloride, and tenofovir disoproxil fumarate