Emtricitabine Rilpivirine And Tenofovir Disoproxil Fumarate + Cyp3a Inducers Interaction
Majorinteraction on record
Description
Coadministration may result in decreased plasma concentrations of rilpivirine and loss of virologic response and possible resistance to rilpivirine or to the class of NNRTIs.
Mechanism
Rilpivirine is primarily metabolized by CYP3A; induction increases clearance
Source: NLP:emtricitabine, rilpivirine hydrochloride, and tenofovir disoproxil fumarate