Empagliflozin Metformin Hydrochloride + Ranolazine Interaction
Majorinteraction on record
Description
OCT2/MATE inhibitor that may increase systemic metformin exposure and increase risk for lactic acidosis.
Mechanism
Interferes with renal tubular transport systems involved in metformin elimination
Source: NLP:empagliflozin, metformin hydrochloride