Empagliflozin Linagliptin Metformin Hydrochloride + Zonisamide Interaction

Majorinteraction on record

Description

Zonisamide causes decreased serum bicarbonate and metabolic acidosis; concomitant use with TRIJARDY XR may increase risk of lactic acidosis.

Mechanism

Carbonic anhydrase inhibition leading to metabolic acidosis

Source: NLP:empagliflozin, linagliptin, metformin hydrochloride

Related drug profiles

All Empagliflozin Linagliptin Metformin Hydrochloride interactions →All Zonisamide interactions →
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