Elexacaftor Tezacaftor And Ivacaftor + Rifampin Interaction

Contraindicatedinteraction on record

Description

Strong CYP3A inducer that significantly decreases ivacaftor AUC by 89%, reducing TRIKAFTA efficacy. Concomitant use not recommended.

Mechanism

CYP3A induction

Source: NLP:elexacaftor, tezacaftor, and ivacaftor