Elexacaftor Tezacaftor And Ivacaftor + Rifampin Interaction
Contraindicatedinteraction on record
Description
Strong CYP3A inducer that significantly decreases ivacaftor AUC by 89%, reducing TRIKAFTA efficacy. Concomitant use not recommended.
Mechanism
CYP3A induction
Source: NLP:elexacaftor, tezacaftor, and ivacaftor