Elexacaftor Tezacaftor And Ivacaftor + Phenytoin Interaction

Contraindicatedinteraction on record

Description

Strong CYP3A inducer expected to decrease elexacaftor, tezacaftor, and ivacaftor exposures, reducing TRIKAFTA efficacy.

Mechanism

CYP3A induction

Source: NLP:elexacaftor, tezacaftor, and ivacaftor