Efgartigimod Alfa + Human Botulinum Neurotoxin Ab Immune Globulin Interaction

Moderateinteraction on record

Description

Concomitant use may lower systemic exposures and reduce effectiveness. Closely monitor for reduced effectiveness; consider discontinuing VYVGART if long-term concomitant use is essential.

Mechanism

VYVGART binds to human neonatal Fc receptor (FcRn), which may lower systemic exposures of FcRn-binding medications

Source: NLP:efgartigimod alfa