Doxepin Hydrochloride + Cimetidine Interaction

Majorinteraction on record

Description

Cimetidine increases doxepin exposure by doubling plasma concentrations. Maximum dose of 3 mg recommended when co-administered.

Mechanism

Nonspecific inhibition of CYP isozymes

Source: NLP:doxepin hydrochloride

Related drug profiles

All Doxepin Hydrochloride interactions →All Cimetidine interactions →
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