Dorzolamide Hydrochloride And Timolol Maleate Ophthalmic Sol + Salicylates Interaction

Moderateinteraction on record

Description

High-dose salicylate therapy may cause acid-base and electrolyte disturbances and associated toxicity when combined with dorzolamide.

Mechanism

Acid-base and electrolyte disturbances from carbonic anhydrase inhibition

Source: NLP:dorzolamide hydrochloride and timolol maleate ophthalmic solution