Diclofenac Sodium + Methotrexate Interaction

Majorinteraction on record

Description

NSAIDs may competitively inhibit methotrexate accumulation and enhance methotrexate toxicity. Caution advised with concomitant use.

Mechanism

Competitive inhibition of methotrexate accumulation

Source: NLP:diclofenac sodium

Related drug profiles

All Diclofenac Sodium interactions →All Methotrexate interactions →
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