Dextroamphetamine Sulfate + Paroxetine Interaction

Majorinteraction on record

Description

CYP2D6 inhibitor and serotonergic drug that increases dextroamphetamine exposure and risk of serotonin syndrome. Initiate with lower doses and monitor for serotonin syndrome.

Mechanism

CYP2D6 inhibition and serotonergic interaction increase exposure and serotonin syndrome risk

Source: NLP:dextroamphetamine sulfate