Dextroamphetamine + Mao Inhibitors Interaction

Contraindicatedinteraction on record

Description

MAOIs slow amphetamine metabolism, increasing norepinephrine release and causing hypertensive crisis, toxic neurological effects, and potentially fatal malignant hyperpyrexia.

Mechanism

Inhibition of amphetamine metabolism leading to increased monoamine release from adrenergic nerve endings

Source: NLP:dextroamphetamine