Deutetrabenazine + Paroxetine Interaction
Majorinteraction on record
Description
Strong CYP2D6 inhibitor that increases systemic exposure to active dihydro-metabolites of deutetrabenazine by approximately 3-fold. Maximum recommended dose should not exceed 36 mg per day.
Mechanism
CYP2D6 inhibition
Source: NLP:deutetrabenazine