Desvenlafaxine Er + Perphenazine Interaction

Moderateinteraction on record

Description

Desvenlafaxine increases perphenazine exposure. Reduce dose by up to one-half with 400 mg desvenlafaxine; no adjustment needed with 100 mg or lower.

Mechanism

CYP2D6 inhibition

Source: NLP:desvenlafaxine er