Darifenacin + Nefazodone Interaction
Majorinteraction on record
Description
Darifenacin systemic exposure is increased with potent CYP3A4 inhibitors; daily dose should not exceed 7.5 mg when co-administered with nefazodone.
Mechanism
CYP3A4 inhibition increases darifenacin exposure
Source: NLP:darifenacin