Cyp3a Inducers + Belumosudil Interaction

Moderateinteraction on record

Description

Strong CYP3A inducers decrease belumosudil exposure and may reduce efficacy. Increase REZUROCK dosage to 200 mg twice daily when used concomitantly.

Mechanism

Belumosudil is a CYP3A substrate

Source: NLP:belumosudil