Cyp Substrates + Linvoseltamab Gcpt Interaction

Moderateinteraction on record

Description

Linvoseltamab-gcpt causes cytokine release that may suppress CYP enzyme activity, increasing CYP substrate exposure and risk of adverse reactions. Monitoring for toxicity recommended.

Mechanism

Cytokine-mediated suppression of cytochrome P450 enzyme activity

Source: NLP:linvoseltamab-gcpt