Cyclosporine + Valsartan And Hydrochlorothiazide Interaction

Moderateinteraction on record

Description

Co-administration of cyclosporine (uptake transporter inhibitor) may increase systemic exposure to valsartan.

Mechanism

Inhibition of hepatic uptake transporter OATP1B1

Source: NLP:valsartan and hydrochlorothiazide