Conjugated Estrogensbazedoxifene + Itraconazole Interaction

Moderateinteraction on record

Description

Strong CYP3A4 inhibitor increases bazedoxifene exposure (40%) and conjugated estrogens exposure (5-9%), potentially increasing drug effects.

Mechanism

CYP3A4 inhibition

Source: NLP:conjugated estrogens/bazedoxifene